BDBM452660 5-methyl-3-((3- ((3R,5R)-5-(1-methyl- 1H-indazol-6- yl)tetrahydrofuran-3-yl)- 1,2,4-oxadiazol-5- yl)methyl)pyrazolo[5,1- f][1,2,4]triazin-4(3H)- one::US10710994, Example 138

SMILES Cc1cnn2ncn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc4cnn(C)c4c3)c(=O)c12

InChI Key InChIKey=OGLFBGKKIABWEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452660   

LigandPNGBDBM452660(5-methyl-3-((3- ((3R,5R)-5-(1-methyl- 1H-indazol-6...)
Affinity DataIC50: 2.30nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandPNGBDBM452660(5-methyl-3-((3- ((3R,5R)-5-(1-methyl- 1H-indazol-6...)
Affinity DataIC50: 8.26nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent