BDBM452675 1-methyl-6-[[3-[rac- (3R,5R)-5-(4- chlorophenyl)tetrahydro- furan-3-yl]-1,2,4- oxadiazol-5-yl]methyl] oxazolo[5,4-d] pyrimidine-2,7-dione::US10710994, Example 153

SMILES Cn1c2c(ncn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc(Cl)cc3)c2=O)oc1=O

InChI Key InChIKey=GFRTYOMOOHPBGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452675   

LigandPNGBDBM452675(1-methyl-6-[[3-[rac- (3R,5R)-5-(4- chlorophenyl)te...)
Affinity DataIC50: 1.80nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandPNGBDBM452675(1-methyl-6-[[3-[rac- (3R,5R)-5-(4- chlorophenyl)te...)
Affinity DataIC50: 6.35nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent