BDBM452676 5-amino-6-[[3-[rac- (3R,5R)-5-(4- fluorophenyl)tetrahydro- furan-3-yl]-1,2,4- oxadiazol-5- yl]methyl]thiazolo[4,5- d]pyrimidin-7-one::US10710994, Example 154

SMILES Nc1nc2ncsc2c(=O)n1Cc1nc(no1)[C@@H]1CO[C@H](C1)c1ccc(F)cc1

InChI Key InChIKey=MXDJEHKNIKUPOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 452676   

LigandPNGBDBM452676(5-amino-6-[[3-[rac- (3R,5R)-5-(4- fluorophenyl)tet...)
Affinity DataIC50: 2.30nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent