BDBM452678 5-amino-1-methyl-6-[[3- [rac-(3R,5R)-5-(4- chlorophenyl)tetrahydro- furan-3-yl]-1,2,4- oxadiazol-5- yl]methyl]triazolo[4,5- d]pyrimidin-7-one::US10710994, Example 156

SMILES Cn1nnc2nc(N)n(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc(Cl)cc3)c(=O)c12

InChI Key InChIKey=DCHZOOHTNLONBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452678   

LigandPNGBDBM452678(5-amino-1-methyl-6-[[3- [rac-(3R,5R)-5-(4- chlorop...)
Affinity DataIC50: 2.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandPNGBDBM452678(5-amino-1-methyl-6-[[3- [rac-(3R,5R)-5-(4- chlorop...)
Affinity DataIC50: 16.1nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent