BDBM452793 1-((3-((1R,5R,6S)-3- (3-fluorophenyl) bicyclo[3.1.0]hex-2- en-6-yl)-1,2,4- oxadiazol-5-yl) methyl)-7-methyl- 1,7-dihydro-6H-::US10711004, Example 115

SMILES Cn1cnc2ncn(Cc3nc(no3)[C@H]3[C@@H]4CC(=C[C@H]34)c3cccc(F)c3)c(=O)c12

InChI Key InChIKey=SSLPGGYMXROYIW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452793   

LigandPNGBDBM452793(1-((3-((1R,5R,6S)-3- (3-fluorophenyl) bicyclo[3.1....)
Affinity DataIC50: 2.30nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandPNGBDBM452793(1-((3-((1R,5R,6S)-3- (3-fluorophenyl) bicyclo[3.1....)
Affinity DataIC50: 9.73nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent