BDBM452973 US10711006, Compound 15i

SMILES Cc1ccc(Oc2ccc(cn2)-c2nn([C@@H]3CCCN(C3)C(=O)C=C)c3ncnc(N)c23)cc1

InChI Key InChIKey=VSQHKYVGRKTWQT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 452973   

TargetTyrosine-protein kinase BTK(Human)
Hangzhou Hertz Pharmaceutical

US Patent
LigandPNGBDBM452973(US10711006, Compound 15i)
Affinity DataIC50: 7.80nMAssay Description:The drug was dissolved in DMSO to make a 10 mM (mmol/L) stock solution, and the stock solution was then diluted to a drug solution with 50× test conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2021
Entry Details
US Patent