BDBM452977 US10711006, Compound 16b

SMILES Nc1ncnc2n(nc(-c3cnc(Oc4ccccc4)c(F)c3)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=RDEBMFROUCPQAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 452977   

TargetTyrosine-protein kinase BTK(Human)
Hangzhou Hertz Pharmaceutical

US Patent
LigandPNGBDBM452977(US10711006, Compound 16b)
Affinity DataIC50: 18.2nMAssay Description:The drug was dissolved in DMSO to make a 10 mM (mmol/L) stock solution, and the stock solution was then diluted to a drug solution with 50× test conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2021
Entry Details
US Patent