BDBM453243 2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)phenoxy)-N-(sec-butyl)acetamide::US10729691, Example 28

SMILES CCC(C)NC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453243   

TargetPutative sugar transporter(malaria parasite P. falciparum)
Kadmon

US Patent
LigandPNGBDBM453243(2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...)
Affinity DataIC50:  55nMAssay Description:Parasite cultures were seeded in 96-well plates (1% hematocrit, 1-2% starting parasitemia, 100 μL total volume) with varying concentrations of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM453243(2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...)
Affinity DataIC50:  55nMAssay Description:HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent