BDBM453352 BDBM553856::US10730826, Compound 42a

SMILES NCCCCC(NC(=O)c1cccnc1)C(=O)COc1c(F)ccc(F)c1F

InChI Key InChIKey=XKWDNMGWBAEXJS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453352   

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM453352(BDBM553856 | US10730826, Compound 42a)
Affinity DataIC50:  0.0600nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain (Kgp) were measured in a fluorogenic assay similar t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM453352(BDBM553856 | US10730826, Compound 42a)
Affinity DataIC50:  0.0600nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent