BDBM453541 2-(5-bromo-6-methoxybenzo[b]thiophene-2- carbonyl)cyclopropane-1-carboxylic acid (Single Enantiomer)::US10730849, Example 6

SMILES COc1cc2sc(cc2cc1Br)C(=O)[C@H]1C[C@H]1C(O)=O

InChI Key InChIKey=QFLXAJNLVZURKV-UHFFFAOYSA-N

Data  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453541   

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453541(2-(5-bromo-6-methoxybenzo[b]thiophene-2- carbonyl)...)
Affinity DataEC50:  703nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
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Date in BDB:
3/21/2021
Entry Details
US Patent