BDBM453547 US10730849, Example 12::tert-butyl 4-(5,6- dimethoxybenzo[b]thiophen-2-yl)-4- oxobutanoate

SMILES COc1cc2cc(sc2cc1OC)C(=O)CCC(=O)OC(C)(C)C

InChI Key InChIKey=SOMAXGSQHFGSLP-UHFFFAOYSA-N

Data  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453547   

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453547(tert-butyl 4-(5,6- dimethoxybenzo[b]thiophen-2-yl)...)
Affinity DataEC50:  5.99E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
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Date in BDB:
3/21/2021
Entry Details
US Patent