BDBM453550 (S)-4-(6-bromo-5- methoxybenzo[b]thiophen-2-yl)-2-methyl-4- oxobutanoic acid::US10730849, Example 15

SMILES COc1cc2cc(sc2cc1Br)C(=O)C[C@H](C)C(O)=O

InChI Key InChIKey=XSPQEYIGQJBPAN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453550   

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453550((S)-4-(6-bromo-5- methoxybenzo[b]thiophen-2-yl)-2-...)
Affinity DataEC50:  894nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453550((S)-4-(6-bromo-5- methoxybenzo[b]thiophen-2-yl)-2-...)
Affinity DataEC50:  894nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent