BDBM453565 (S)-4-(5-fluoro-6- methoxybenzo[b] thiophen- 2-yl)-2-methyl- 4-oxobutanoic acid::US10730849, Example 30

SMILES COc1cc2sc(cc2cc1F)C(=O)C[C@H](C)C(O)=O

InChI Key InChIKey=HKTRKFSSRALDQW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453565   

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453565((S)-4-(5-fluoro-6- methoxybenzo[b] thiophen- 2-yl)...)
Affinity DataEC50:  5.05E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453565((S)-4-(5-fluoro-6- methoxybenzo[b] thiophen- 2-yl)...)
Affinity DataEC50:  1.87E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent