BDBM453582 (2S)-4-(6-methoxy-5-propyl-1- benzothiophen-2-yl)-2-methyl-4- oxobutanoic acid::US10730849, Example 47

SMILES CCCc1cc2cc(sc2cc1OC)C(=O)C[C@H](C)C(O)=O

InChI Key InChIKey=CJVQPXBNMSTNIN-UHFFFAOYSA-N

Data  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453582   

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453582((2S)-4-(6-methoxy-5-propyl-1- benzothiophen-2-yl)-...)
Affinity DataEC50:  5.06E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
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Date in BDB:
3/21/2021
Entry Details
US Patent