BDBM453712 Ethyl 2-(9-ethyl-8-fluoro-6-methyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-1H-benzimidazole-5-carboxylate::US10730856, Example 9

SMILES CCOC(=O)c1ccc2n(CCOC)c(nc2c1)-c1ccc2n(CC)c3c(F)cc(C)cc3c2c1

InChI Key InChIKey=XMIMARJGIKBQIF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453712   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453712(Ethyl 2-(9-ethyl-8-fluoro-6-methyl-9H-carbazol-3-y...)
Affinity DataIC50: 62nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent