BDBM454580 US10717746, Example 60

SMILES CC(=O)N[C@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CCC(C)(C)Cc23)c(Cl)cn1

InChI Key InChIKey=VMEQVKSLIMZPDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 454580   

TargetCyclin-dependent kinase 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM454580(US10717746, Example 60)
Affinity DataIC50: 3nMAssay Description:Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM454580(US10717746, Example 60)
Affinity DataIC50: 17nMAssay Description:Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent