BDBM454669 (S)-6-((1-amino-1-oxopropan-2- yl)amino)-2-(1-isobutyl-1H-indol-5- yl)pyrimidine-4-carboxamide::US10730866, Compound 47

SMILES CC(C)Cn1ccc2cc(ccc12)-c1nc(N[C@@H](C)C(N)=O)cc(n1)C(N)=O

InChI Key InChIKey=GUYLBCMFEKTREH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 454669   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM454669((S)-6-((1-amino-1-oxopropan-2- yl)amino)-2-(1-isob...)
Affinity DataIC50: 4.19E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent