BDBM454671 (S)-1-(2-(1-(4- (trifluoromethyl)phenyl)-1H- benzo[d]imidazol-6-yl)pyrimidin-4- yl)ethane-1,2-diol::US10730866, Compound 51

SMILES OC[C@@H](O)c1ccnc(n1)-c1ccc2ncn(-c3ccc(cc3)C(F)(F)F)c2c1

InChI Key InChIKey=AMJUMDUMMZCIOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 454671   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM454671((S)-1-(2-(1-(4- (trifluoromethyl)phenyl)-1H- benzo...)
Affinity DataIC50: 3.51E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent