BDBM454700 (S)-1-(6-(2-(4- (trifluoromethyl)benzyl)-2H-indazol- 5-yl)pyridin-2-yl)ethane-1,2-diol::US10730866, Compound 108

SMILES OC[C@@H](O)c1cccc(n1)-c1ccc2nn(Cc3ccc(cc3)C(F)(F)F)cc2c1

InChI Key InChIKey=MFVBDWIHPSKLHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 454700   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM454700((S)-1-(6-(2-(4- (trifluoromethyl)benzyl)-2H-indazo...)
Affinity DataIC50: 4.68E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent