BDBM454701 (S)-1-(6-(1-(4- (trifluoromethyl)benzyl)-1H-indol-5- yl)pyridin-2-yl)ethane-1,2-diol::US10730866, Compound 109

SMILES OC[C@@H](O)c1cccc(n1)-c1ccc2n(Cc3ccc(cc3)C(F)(F)F)ccc2c1

InChI Key InChIKey=ZXHLSDRTXYMOKO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 454701   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM454701((S)-1-(6-(1-(4- (trifluoromethyl)benzyl)-1H-indol-...)
Affinity DataIC50: 177nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent