BDBM454705 (S)-6-((1-amino-1-oxopropan-2- yl)amino)-2-(1-(cyclohexylmethyl)- 1H-indol-5-yl)pyrimidine-4- carboxamide::US10730866, Compound 113

SMILES C[C@H](Nc1cc(nc(n1)-c1ccc2n(CC3CCCCC3)ccc2c1)C(N)=O)C(N)=O

InChI Key InChIKey=AVZDJOHDYASLAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 454705   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM454705((S)-6-((1-amino-1-oxopropan-2- yl)amino)-2-(1-(cyc...)
Affinity DataIC50: 4.43E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent