BDBM454718 6-amino-2-(benzofuran-5-yl)-N-(4- (trifluoromethyl)phenyl)pyrimidine-4- carboxamide::US10730866, Compound 138

SMILES Nc1cc(nc(n1)-c1ccc2occc2c1)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=VZYKPIBJXQJXSN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 454718   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM454718(6-amino-2-(benzofuran-5-yl)-N-(4- (trifluoromethyl...)
Affinity DataIC50: 3.66E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent