BDBM454728 (2R,3S)-3-(6-(1-(cyclohexylmethyl)- 1H-indol-5-yl)pyridin-2-yl)-2,3- dihydroxypropanamide::US10730866, Compound 152

SMILES NC(=O)[C@H](O)[C@@H](O)c1cccc(n1)-c1ccc2n(CC3CCCCC3)ccc2c1

InChI Key InChIKey=MBYIQXSLRMDZQJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 454728   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM454728((2R,3S)-3-(6-(1-(cyclohexylmethyl)- 1H-indol-5-yl)...)
Affinity DataIC50: 402nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent