BDBM455373 ((R)-1-Phenyl-ethyl)-[6-::US10730882, Example 8

SMILES C[C@H](c1ccccc1)N(C)c1ncc2cc(-c3ncnc4[nH]ncc34)ccc2n1

InChI Key InChIKey=MLOMCGJRDMXOAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455373   

TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 455373BDBM455373(US10730882, Example 8 | ((R)-1-Phenyl-ethyl)-[6-)
Affinity DataIC50: 108nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent