BDBM455454 US20260116867, Compound M8

SMILES COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(NC(=O)CNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)cc(C(C)(C)C)c3)c2C)c1

InChI Key InChIKey=YZHXWHSTPGNHKE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455454   

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 455454BDBM455454(US20260116867, Compound M8)
Affinity DataEC50:  15nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent