BDBM456480 US10723742, Example 206::US10723742, Example 225::US11510915, Example 225

SMILES CCC(O)(CC)Cn1ncc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2

InChI Key InChIKey=OTQUVMAHLBKNQO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 456480   

TargetLysine-specific histone demethylase 1A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM456480(US10723742, Example 225 | US10723742, Example 206 ...)
Affinity DataIC50: 0.200nMAssay Description:The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM456480(US10723742, Example 225 | US10723742, Example 206 ...)
Affinity DataIC50: 0.200nMAssay Description:The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2021
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM456480(US10723742, Example 225 | US10723742, Example 206 ...)
Affinity DataIC50: 0.300nMAssay Description:The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM456480(US10723742, Example 225 | US10723742, Example 206 ...)
Affinity DataIC50: 0.300nMAssay Description:The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2021
Entry Details
US Patent