BDBM456742 US10736883, Example 212.0::US10736883, Example 216.0

SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](O)c2ncc(Cl)cn2)nnc1-c1ccc(C)o1

InChI Key InChIKey=LWQDLRMWJKVHSW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 456742   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM456742(US10736883, Example 216.0 | US10736883, Example 21...)
Affinity DataEC50:  0.0740nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM456742(US10736883, Example 216.0 | US10736883, Example 21...)
Affinity DataEC50:  0.230nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent