BDBM456844 US10736883, Example 321.0

SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@H]2C[C@@H](O)CN(C2)c2cncc(n2)C#N)nnc1-c1ccc(C)o1

InChI Key InChIKey=NDWWNVVSXWZVLJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 456844   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM456844(US10736883, Example 321.0)
Affinity DataEC50:  0.180nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent