BDBM456902 US10736890, Compound TABLE B.12

SMILES CN1CCC23[C@H](CCC[C@H]2C1)Oc1c3cccc1O

InChI Key InChIKey=MMWJAJXGSUFPKC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 456902   

TargetMu-type opioid receptor(Human)
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM456902(US10736890, Compound TABLE B.12)
Affinity DataKi:  0.490nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM456902(US10736890, Compound TABLE B.12)
Affinity DataIC50: 74nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent