BDBM456947 US10738007, Compound ID 10::US11555039, Compound ID 10

SMILES OC[C@@H](NC(=O)c1ccc(cc1)-c1ccncc1)c1cccc(c1)C(=O)NC1CCCC1

InChI Key InChIKey=AZLYARWHEXPDEW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 456947   

TargetRho-associated protein kinase 2(Human)
Translational Drug Development

US Patent
LigandPNGBDBM456947(US10738007, Compound ID 10 | US11555039, Compound ...)
Affinity DataIC50: 0.870nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Translational Drug Development

US Patent
LigandPNGBDBM456947(US10738007, Compound ID 10 | US11555039, Compound ...)
Affinity DataIC50: 0.870nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Translational Drug Development

US Patent
LigandPNGBDBM456947(US10738007, Compound ID 10 | US11555039, Compound ...)
Affinity DataIC50: 4.80nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Translational Drug Development

US Patent
LigandPNGBDBM456947(US10738007, Compound ID 10 | US11555039, Compound ...)
Affinity DataIC50: 4.80nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent