BDBM457123 US10738009, Compound 87

SMILES COc1c(C)cccc1Oc1cc(ccc1C(=O)Nc1cc(=O)[nH]cc1C)C(F)(F)F

InChI Key InChIKey=ZCHPVWZDQCVUSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 457123   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM457123(US10738009, Compound 87)
Affinity DataIC50: 27nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent