BDBM457549 US10738056, Compound C1270

SMILES Cc1[nH]c2c(c(nn2c(=O)c1-c1ncco1)C#N)-c1ccccc1

InChI Key InChIKey=UKFMVEABSQJMCK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 457549   

TargetCyclic GMP-AMP synthase [155-522](Human)
Aduro Biotech

US Patent
LigandPNGBDBM457549(US10738056, Compound C1270)
Affinity DataIC50: 20nMAssay Description:Protein was expressed and purified from E. coli BL21 DE3 Rosetta 2 (EMD Millipore) cells using standard techniques. Cells were grown in 2x yeast extr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent