BDBM457705 2-(3-(8-Amino-6- (1-methyl-1H- pyrazol-4- yl)imidazo[1,2- a]pyrazin-3-yl)-4- methylphenyl)- 3,3,3- trifluoropropane-::US10738057, Example 69

SMILES CC(c1ccc(C)c(c1)-c1cnc2c(N)nc(cn12)-c1cnn(C)c1)C(F)(F)F

InChI Key InChIKey=AIMKXSTYOWFMRW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457705   

LigandPNGBDBM457705(2-(3-(8-Amino-6- (1-methyl-1H- pyrazol-4- yl)imida...)
Affinity DataIC50: 100nMAssay Description:PI3K-γ: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from PerkinElmer (Waltham, Mass.)....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandPNGBDBM457705(2-(3-(8-Amino-6- (1-methyl-1H- pyrazol-4- yl)imida...)
Affinity DataIC50: 100nMAssay Description:PI3Kδ: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from PerkinElmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent