BDBM457796 2-amino-9- [(1R,6R,8R,9R,14S,16R,17R,18R)-17- amino-16-(6-amino-9H-purin-9-yl)- 3,11,18-trihydroxy-3,11-dioxido- 2,4,7,10,12,15-hexaoxa-3,11- diphosphatricyclo[12.2.1.16,9]octadec- 8-yl]-1,9-dihydro-6H-purin-6-one::US10738074, Example 33

SMILES N[C@@H]1[C@H]2COP(O)(=O)O[C@@H]3[C@H](O)[C@@H](COP(O)(=O)O[C@H]1[C@@H](O2)n1cnc2c(N)ncnc12)O[C@H]3n1cnc2c1nc(N)[nH]c2=O

InChI Key InChIKey=LPONDLBRNVCRKB-UHFFFAOYSA-N

Data  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 457796   

LigandPNGBDBM457796(2-amino-9- [(1R,6R,8R,9R,14S,16R,17R,18R)-17- amin...)
Affinity DataEC50:  1.60nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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Date in BDB:
4/4/2021
Entry Details
US Patent