BDBM457828 US10738063, Example 58
SMILES Cc1cc(Cl)c(F)cc1-c1c2OCC(F)(F)Cn2nc1C(=O)NC1CC1
InChI Key InChIKey=GILOGFJUMQAJNQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 457828
Affinity DataIC50: 8.52nMAssay Description:Human PDE4B1 coding sequence (amino acids 122 to 736 from the sequence with accession number Q07343) with the mutations resulting in the amino acid s...More data for this Ligand-Target Pair
TargetIsoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) 0-562](Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 156nMAssay Description:A portion of the human PDE4D3 coding sequence (amino acids 50 to 672 from the sequence with accession number Q08499-2) was cloned into the baculoviru...More data for this Ligand-Target Pair
Affinity DataIC50: 16.4nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair