BDBM458104 US10752613, Compound Formula (Ig)

SMILES O=C(Nc1ccc(-c2c[nH]nn2)c(C(F)(F)F)c1)c1c(O)[nH]c(=O)[nH]c1=O

InChI Key InChIKey=NIMHXWTUGLBWBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458104   

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 458104BDBM458104(US10752613, Compound Formula (Ig))
Affinity DataIC50: 2.20E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 458104BDBM458104(US10752613, Compound Formula (Ig))
Affinity DataIC50: 2.70E+3nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
US Patent