BDBM458480 US10744128, Compound 66

SMILES CC(C)N1CCC(CC1)n1cc(cn1)C(=O)Nc1cc2cc(ccc2cn1)-c1nnc(C)s1

InChI Key InChIKey=TUCZNPDKRGNQFB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458480   

LigandPNGBDBM458480(US10744128, Compound 66)
Affinity DataEC50:  4nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Divis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Samumed

US Patent
LigandPNGBDBM458480(US10744128, Compound 66)
Affinity DataEC50:  390nMAssay Description:Briefly, recombinant GSK3β kinase, ATP and Ser/Thr peptide 09 are prepared in 1× Kinase buffer to final concentrations of 0.04 μg/mL, 46 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent