BDBM459202 2-[1-[2-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenteno[c]furan5-oxy)-2-(2-methoxyphenyl)ethyl)-5-methyl-6-oxazol-2-yl-2,4-dioxo-thieno[2,3-d]pyrimid-3-yl]-2-methyl-propanoic acid::US10759812, Example 13

SMILES COc1ccccc1C(Cn1c2sc(c(C)c2c(=O)n(c1=O)C(C)(C)C(O)=O)-c1ncco1)OC1CC2COCC2C1

InChI Key InChIKey=RSQXZBGTONJBGQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459202   

TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459202(2-[1-[2-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenteno[c...)
Affinity DataIC50:  4.24nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459202(2-[1-[2-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenteno[c...)
Affinity DataIC50:  1.76nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent