BDBM459204 2-[1-[2-[(5-cyano-1,2,3,3a,4,5,6,6a-octahydropentalen-2-yl)oxy]-2-(2-methoxyphenyl)ethyl]-5-methyl-6-oxazol-2-yl-2,4-dioxo-thieno[2,3-d]pyrimid-3-yl]-2-methyl-propanoic acid::US10759812, Example 15

SMILES COc1ccccc1C(Cn1c2sc(c(C)c2c(=O)n(c1=O)C(C)(C)C(O)=O)-c1ncco1)O[C@H]1C[C@H]2CC(C[C@H]2C1)C#N

InChI Key InChIKey=VNDXEFZISIXRBJ-GDZFOEBASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459204   

TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459204(2-[1-[2-[(5-cyano-1,2,3,3a,4,5,6,6a-octahydropenta...)
Affinity DataIC50:  6.53nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459204(2-[1-[2-[(5-cyano-1,2,3,3a,4,5,6,6a-octahydropenta...)
Affinity DataIC50:  1.64nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent