BDBM461507 US10774071, Example A-83

SMILES COc1nc(N[C@H]2CCc3c2cccc3-c2cccc(c2Cl)-c2ccc(CNC[C@H]3C[C@](C)(O)C3)c(OC)n2)c(cc1CN[C@@H](C)C(O)=O)C(F)(F)F

InChI Key InChIKey=CDYAVCGSRRASIQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 461507   

LigandPNGBDBM461507(US10774071, Example A-83)
Affinity DataIC50: 0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
US Patent

LigandPNGBDBM461507(US10774071, Example A-83)
Affinity DataEC50:  46nMAssay Description:Compounds were tested in a functional co-culture reporter assay in which TCR-mediated NFAT activity is inhibited by the engagement of PD-1 with PD-L1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
US Patent