BDBM462769 US10780090, Compound I-101::{(1R,2R,3R,4R)-4-[(5-{[4-(3-bromobenzyl)-2-thienyl]carbonyl}pyrimidin-4-yl)amino]- 3-fluoro-2-hydroxycyclopentyl}methyl sulfamate

SMILES NS(=O)(=O)OC[C@H]1C[C@@H](Nc2ncncc2C(=O)c2cc(Cc3cccc(Br)c3)cs2)[C@@H](F)[C@@H]1O

InChI Key InChIKey=SLWMYANJWPBDSJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462769   

TargetSUMO-activating enzyme subunit 1(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM462769(US10780090, Compound I-101 | {(1R,2R,3R,4R)-4-[(5-...)
Affinity DataIC50: 10nMAssay Description:The SAE enzymatic reaction totals 50 μl and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 5 mM MgCl2, 0.5 μM ATP, 250 μM GSH, 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2021
Entry Details
US Patent