BDBM463163 4-Amino-2-{8-[(3- fluorophenyl)methyl]imidazo[1,2- a]pyrazin-6-yl}-5-(3-hydroxy-4- (trifluoromethyl)phenyl)-5- methyl-5,7-dihydro-6H- pyrrolo[2,3-d]pyrimidin-6-one::US10780092, Example 17-B

SMILES CC1(C(=O)Nc2nc(nc(N)c12)-c1cn2ccnc2c(Cc2cccc(F)c2)n1)c1ccc(c(O)c1)C(F)(F)F

InChI Key InChIKey=GDZUFJWEVBVZRR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 463163   

TargetGuanylate cyclase soluble subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM463163(4-Amino-2-{8-[(3- fluorophenyl)methyl]imidazo[1,2-...)
Affinity DataKi:  0.163nMAssay Description:The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...More data for this Ligand-Target Pair
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Date in BDB:
5/2/2021
Entry Details
US Patent