BDBM463638 US10781204, Compound I-117

SMILES CN(C)[C@H]1CC[C@@H](CC1)Oc1ccn(n1)-c1cc(nc2CNC(=O)c12)-c1c(F)cccc1C#N

InChI Key InChIKey=YHLGKVZOIAECOR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 463638   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM463638(US10781204, Compound I-117)
Affinity DataKi:  5nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM463638(US10781204, Compound I-117)
Affinity DataKi:  55nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent