BDBM463786 US10781209, Example 24B

SMILES COc1cc(-c2cn(C)c(=O)c3[nH]ccc23)c2c(c1)N(C)C[C@@H](c1ccccc1)O2

InChI Key InChIKey=GCUFENZVZMDQEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 463786   

TargetBromodomain-containing protein 4 [75-147](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 463786BDBM463786(US10781209, Example 24B)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent

TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 463786BDBM463786(US10781209, Example 24B)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent