BDBM464281 3-(5-(1H-pyrazol-4- yl)pyridin-2-yl)-1-(3- methoxybenzyl)-8-(2- methoxyethyl)-1,3,8- triazaspiro[4.5]decan- 2-one::US10787450, Example 162
SMILES COCCN1CCC2(CN(C(=O)N2Cc2cccc(OC)c2)c2ccc(cn2)-c2cn[nH]c2)CC1
InChI Key InChIKey=XDOVUICQYAUBLU-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464281
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair