BDBM464287 2-(3-(4-(1H-pyrazol- 4-yl)phenyl)-1-(3- methoxybenzyl)-2- oxo-1,3,8- triazaspiro[4.5]decan- 8-yl)acetamide::US10787450, Example 169
SMILES COc1cccc(CN2C(=O)N(CC22CCN(CC(N)=O)CC2)c2ccc(cc2)-c2cn[nH]c2)c1
InChI Key InChIKey=ZQNVLZQMUOPKFC-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464287
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair