BDBM465566 US10793568, Compound I-216

SMILES CC(CCS(=O)(=O)NC(=O)c1ccc(cc1)N1C[C@@H]2C[C@H]1C[C@H]2OCc1c(onc1-c1c(Cl)cccc1Cl)C1CC1)OC(C)=O

InChI Key InChIKey=BASNFTLGOCATQN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465566   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM465566(US10793568, Compound I-216)
Affinity DataEC50:  0.398nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent