BDBM466682 US10800761, Example 1::US11731958, Example 1
SMILES COc1cccc(F)c1-c1nccc(n1)C(=O)Nc1cc(F)ccc1N1C[C@H]2C[C@@H]1CN2
InChI Key InChIKey=JKHBVOCOHYSWTQ-HUUCEWRRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 466682
Affinity DataKi: 2.20nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Affinity DataKi: 541nMAssay Description:Inhibitory activity against human carbonic anhydrase II using pH stat assayMore data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Compound was evaluated for the inhibition of Escherichia coli Thymidylate SynthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 104nMAssay Description:Histamine H2 receptor antagonism on the right atrium of the guinea pigMore data for this Ligand-Target Pair
Affinity DataIC50: 1.69E+3nMAssay Description:The compound was tested for alpha-adrenergic activity against Alpha-1 adrenergic receptor from rat aorta.More data for this Ligand-Target Pair