BDBM466728 US10800761, Example 47::US11731958, Example 47
SMILES COc1cccc(F)c1-c1nccc(n1)C(=O)Nc1ccc(cc1N1C[C@@H](N)C[C@H]1CO)-c1c(cnn1C)C#N
InChI Key InChIKey=WAWDCCVZPCGIJC-OALUTQOASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 466728
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Inhibitory activity against human carbonic anhydrase II using pH stat assayMore data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:In vitro for inhibition of rat HMG-CoA reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+3nMAssay Description:Compound was evaluated for the inhibition of human Thymidylate SynthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:Histamine H2 receptor antagonism on the right atrium of the guinea pigMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human carbonic anhydrase II using pH stat assayMore data for this Ligand-Target Pair