BDBM467252 7-amino-3-(1-(but-2-ynoyl)pyrrolidin-3-yl)-1-(4-phenoxyphenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyridazin-4-one ::US10800785, Example 6

SMILES CC#CC(=O)N1CCC(C1)c1nn(-c2ccc(Oc3ccccc3)cc2)c2c(N)n[nH]c(=O)c12

InChI Key InChIKey=HJDPBZHQPSKGJQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 467252   

TargetTyrosine-protein kinase BTK(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM467252(7-amino-3-(1-(but-2-ynoyl)pyrrolidin-3-yl)-1-(4-ph...)
Affinity DataIC50: 179nMAssay Description:MTS testing kit was purchased from Promega. The DMEM, Fetal bovine serum and Penicillin-Streptomycin were purchased from Gibco. Dimethyl sulfoxide (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent